Viral Infection Spreading and Mutation in Cell Culture

A new model of viral infection spreading in cell cultures is proposed taking into account virus mutation. This represents a reaction-diffusion system equations with time delay for the concentrations uninfected cells, infected cells and load. Infection progression characterized by replication number Rv, which determines total Analytical formulas speed propagation load are obtained confirmed numerical simulations. It shown that mutation leads to emergence variant. Conditions coexistence two variants or competitive exclusion one them found, different stages identified.